BDBM50262685 6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine::6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine::CHEMBL478629::Dorsomorphin::US9040694, Dorsomorphin

SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1

InChI Key InChIKey=XHBVYDAKJHETMP-UHFFFAOYSA-N

Data  41 IC50  3 EC50

PDB links: 7 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262685   

TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL

LigandBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)Copy SMILESCopy InChI

Affinity DataIC50:  430nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI